A Monoclonal Antibody Against α V β 3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs-Reference-Cited by-同舟云学术

A Monoclonal Antibody Against α V β 3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs

Published:2010-02-10 Issue:18 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Maile Laura A.¹,Busby Walker H.¹,Nichols Timothy C.²,Bellinger Dwight A.³,Merricks Elizabeth P.²,Rowland Michael¹,Veluvolu Umadevi¹,Clemmons David R.¹

Affiliation:

1. Division of Endocrinology, University of North Carolina, Chapel Hill, NC 27599-7170, USA.

2. Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599-7170, USA.

3. Division of Laboratory Animal Medicine, University of North Carolina, Chapel Hill, NC 27599-7170, USA.

Abstract

An antibody directed at the C terminus of an integrin subunit can prevent the formation of atherosclerotic lesions in diabetic pigs.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference51 articles.

1. Screening for Coronary Artery Disease in Patients With Diabetes

2. The importance of treating multiple cardiometabolic risk factors in patients with Type 2 diabetes

3. Targeted Overexpression of IGF-I in Smooth Muscle Cells of Transgenic Mice Enhances Neointimal Formation through Increased Proliferation and Cell Migration after Intraarterial Injury

4. Protease-Resistant Insulin-Like Growth Factor (IGF)-Binding Protein-4 Inhibits IGF-I Actions and Neointimal Expansion in a Porcine Model of Neointimal Hyperplasia

5. Expression, Regulation, and Function of IGF-1, IGF-1R, and IGF-1 Binding Proteins in Blood Vessels

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