Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing-Reference-Cited by-同舟云学术

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

Published:2011-09-14 Issue:100 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Martino Mikaël M.¹,Tortelli Federico¹,Mochizuki Mayumi¹,Traub Stephanie²,Ben-David Dror³,Kuhn Gisela A.⁴,Müller Ralph⁴,Livne Erella³,Eming Sabine A.²⁵,Hubbell Jeffrey A.¹⁶

Affiliation:

1. Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

2. Department of Dermatology, University of Cologne, 50931 Cologne, Germany.

3. Department of Anatomy and Cell Biology, Faculty of Medicine, Technion-Israel Institute of Technology, 31096 Haifa, Israel.

4. Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.

5. Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.

6. Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Abstract

A multifunctional fibronectin fragment enhances the regenerative effects of growth factors in vivo in animal models of chronic wounds and critical-size bone defects.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. Bone morphogenetic proteins in orthopaedic surgery

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