Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans-Reference-Cited by-同舟云学术

Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans

Published:2014-10 Issue:256 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Kobayakawa Kazu¹²,Kumamaru Hiromi¹²,Saiwai Hirokazu¹²,Kubota Kensuke¹²,Ohkawa Yasuyuki¹,Kishimoto Junji³,Yokota Kazuya¹²,Ideta Ryosuke⁴,Shiba Keiichiro⁵,Tozaki-Saitoh Hidetoshi⁶,Inoue Kazuhide⁶,Iwamoto Yukihide²,Okada Seiji¹²

Affiliation:

1. Department of Advanced Medical Initiatives, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

2. Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

3. Department of Medical Informatics, Kyushu University, Fukuoka 812-8582, Japan.

4. Department of Rehabilitation, Spinal Injuries Center, Izuka 820-8508, Japan.

5. Department of Orthopaedic Surgery, Spinal Injuries Center, Izuka 820-8508, Japan.

6. Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Abstract

Acute hyperglycemia exacerbates poor functional outcomes after spinal cord injury through overactivation of microglia in mice and in a human cohort.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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