Therapeutic Targeting of SPINK1-Positive Prostate Cancer-Reference-Cited by-同舟云学术

Therapeutic Targeting of SPINK1-Positive Prostate Cancer

Published:2011-03-02 Issue:72 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ateeq Bushra¹²,Tomlins Scott A.¹²,Laxman Bharathi¹²,Asangani Irfan A.¹²,Cao Qi¹²,Cao Xuhong¹³,Li Yong¹²,Wang Xiaoju¹²,Feng Felix Y.¹⁴⁵,Pienta Kenneth J.¹⁵⁶,Varambally Sooryanarayana¹²⁵,Chinnaiyan Arul M.¹²³⁵⁷

Affiliation:

1. Michigan Center for Translational Pathology, Ann Arbor, MI 48109, USA.

2. Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.

3. Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

4. Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.

5. Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

6. Department of Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

7. Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA.

Abstract

SPINK1 is a therapeutic target in a subset of patients with SPINK1 + /ETS − prostate cancer.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference35 articles.

1. Cancer Statistics, 2010

2. Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 Gene Fusions in Prostate Cancer

3. Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

4. TMPRSS2:ETV4 Gene Fusions Define a Third Molecular Subtype of Prostate Cancer

5. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

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