Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis-Reference-Cited by-同舟云学术

Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

Published:2012-10-31 Issue:158 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Motta Jean-Paul¹²³,Bermúdez-Humarán Luis G.⁴,Deraison Céline¹²³,Martin Laurence¹²³,Rolland Corinne¹²³,Rousset Perrine¹²³,Boue Jérôme¹²³,Dietrich Gilles¹²³,Chapman Kevin⁵,Kharrat Pascale⁴,Vinel Jean-Pierre³⁶,Alric Laurent³⁶,Mas Emmanuel¹²³⁷,Sallenave Jean-Michel⁸⁹¹⁰,Langella Philippe⁴,Vergnolle Nathalie¹²³⁵

Affiliation:

1. INSERM, U1043, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse F-31300, France.

2. CNRS, U5282, Toulouse F-31300, France.

3. CPTP, Université de Toulouse, Université Paul Sabatier (UPS), Toulouse F-31300, France.

4. Institut National de la Recherche Agronomique (INRA), UMR 1319 Micalis, Commensal and Probiotics-Host Interactions Laboratory, Domaine de Vilvert, 78352 Jouy-en-Josas Cedex, France.

5. Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

6. Pôle Digestif, CHU Purpan, Toulouse F-31059, France.

7. Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital, Toulouse F-31059, France.

8. Institut Pasteur, Unité de Défense Innée et Inflammation, Paris F-75015, France.

9. INSERM U874, Paris F-75724, France.

10. Universite Paris Diderot, Sorbonne Paris Cite, Cellule Pasteur F-75013, France.

Abstract

Lactic acid–producing bacteria engineered to produce the antiprotease Elafin restore colon homeostasis in mice with colitis and protect human tissue from inflammation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference33 articles.

1. CLINICAL RELEVANCE OF PROTEINASE ACTIVATED RECEPTORS (PARS) IN THE GUT

2. Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis

3. Protease-activated receptors as drug targets in inflammation and pain

4. Review article: proteinase-activated receptors - novel signals for gastrointestinal pathophysiology

5. Role for protease activity in visceral pain in irritable bowel syndrome

Cited by 203 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Versatile whey acidic protein four-disulfide core domain proteins: biology and role in diseases;Frontiers in Cell and Developmental Biology;2024-09-04

2. Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2;Gut Microbes;2024-08-22

3. Next generation probiotics for human health: An emerging perspective;Heliyon;2024-08

4. Toward Practical Applications of Engineered Living Materials with Advanced Fabrication Techniques;ACS Synthetic Biology;2024-07-13

5. W-GA nanodots restore intestinal barrier functions by regulating flora disturbance and relieving excessive oxidative stress to alleviate colitis;Acta Biomaterialia;2024-07