Human Melanoma Metastasis in NSG Mice Correlates with Clinical Outcome in Patients-Reference-Cited by-同舟云学术

Human Melanoma Metastasis in NSG Mice Correlates with Clinical Outcome in Patients

Published:2012-11-07 Issue:159 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Quintana Elsa¹,Piskounova Elena²,Shackleton Mark¹,Weinberg Daniel¹,Eskiocak Ugur²,Fullen Douglas R.³,Johnson Timothy M.⁴,Morrison Sean J.¹²

Affiliation:

1. Howard Hughes Medical Institute, Life Sciences Institute, Department of Internal Medicine, and Center for Stem Cell Biology, University of Michigan, Ann Arbor, MI 48109–2216, USA.

2. Children’s Research Institute, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

3. Department of Pathology, University of Michigan, Ann Arbor, MI 48109–2216, USA.

4. Department of Dermatology, University of Michigan, Ann Arbor, MI 48109–2216, USA.

Abstract

The ability of melanomas to produce circulating tumor cells and to metastasize in immunocompromised mice correlates with their ability to form distant metastases in patients.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference30 articles.

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3. Predicting Clinical Outcome through Molecular Profiling in Stage III Melanoma

4. The gene expression signatures of melanoma progression

5. Integrative Genome Comparison of Primary and Metastatic Melanomas

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