Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel-Reference-Cited by-同舟云学术

Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel

Published:2021-12-22 Issue:625 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Le Clec’h Winka¹^ORCID,Chevalier Frédéric D.¹^ORCID,Mattos Ana Carolina A.²^ORCID,Strickland Amanda¹^ORCID,Diaz Robbie¹,McDew-White Marina¹,Rohr Claudia M.³^ORCID,Kinung’hi Safari⁴,Allan Fiona⁵⁶^ORCID,Webster Bonnie L.⁵⁶^ORCID,Webster Joanne P.⁵⁷^ORCID,Emery Aidan M.⁵⁶^ORCID,Rollinson David⁵⁶^ORCID,Djirmay Amadou Garba⁸⁹,Al Mashikhi Khalid M.¹⁰^ORCID,Al Yafae Salem¹⁰,Idris Mohamed A.¹¹^ORCID,Moné Hélène¹²^ORCID,Mouahid Gabriel¹²^ORCID,LoVerde Philip²,Marchant Jonathan S.³^ORCID,Anderson Timothy J. C.¹^ORCID

Affiliation:

1. Texas Biomedical Research Institute, San Antonio, TX 78227, USA.

2. University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

3. Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

4. National Institute for Medical Research, Mwanza, United Republic of Tanzania.

5. London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.

6. Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK.

7. Centre for Emerging, Endemic and Exotic Diseases (CEEED), Royal Veterinary College, University of London, London, UK.

8. Réseau International Schistosomiases Environnemental Aménagement et Lutte (RISEAL), Niamey, Niger.

9. World Health Organization, Geneva, Switzerland.

10. Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman.

11. Sultan Qaboos University, Muscat, Sultanate of Oman.

12. Host-Pathogen-Environment Interactions Laboratory, University of Perpignan, Perpignan, France.

Abstract

A transient receptor potential channel in Schistosoma mansoni determines variation in praziquantel response.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference81 articles.

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3. Schistosomiasis

4. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

5. Schistosomiasis: Still a cause of significant morbidity and mortality;Verjee M. A.;Res. Rep. Trop. Med.,2019

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