A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy-Reference-Cited by-同舟云学术

A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy

Published:2019-03-20 Issue:484 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Weedall Gareth D.¹²,Mugenzi Leon M. J.³⁴,Menze Benjamin D.¹³⁴,Tchouakui Magellan³⁴,Ibrahim Sulaiman S.¹⁵,Amvongo-Adjia Nathalie⁴⁶^ORCID,Irving Helen¹,Wondji Murielle J.¹³⁴,Tchoupo Micareme³⁴,Djouaka Rousseau⁷,Riveron Jacob M.¹³⁴^ORCID,Wondji Charles S.¹³⁴^ORCID

Affiliation:

1. Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.

2. School of Natural Sciences and Psychology, Liverpool John Moores University, Liverpool L3 3AF, U.K.

3. LSTM Research Unit at the Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), P.O. Box 288, Yaoundé, Cameroon.

4. Centre for Research in Infectious Diseases (CRID), P.O. Box 13591, Yaoundé, Cameroon.

5. Department of Biochemistry, Bayero University, PMB 3011, Kano, Nigeria.

6. Centre for Medical Research, Institute of Medical Research and Medicinal Plants Studies (IMPM), P.O. Box 13033, Yaoundé, Cameroon.

7. International Institute of Tropical Agriculture (IITA), Cotonou 08 BP 0932, Benin.

Abstract

A cytochrome P450 DNA marker in a major mosquito vector of malaria indicates that pyrethroid resistance reduces bednet efficacy.

Funder

Wellcome Trust

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference50 articles.

1. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

2. The way forward for vector control

3. Insecticide Resistance in Insect Vectors of Human Disease

4. Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s.

5. W. G. M. Programme Global Plan for Insecticide Resistance Management (GPIRM) (World Health Organization Geneva Switzerland 2012).

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