Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models-Reference-Cited by-同舟云学术

Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models

Published:2021-09-15 Issue:611 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Schneider Marcel André¹^ORCID,Heeb Laura¹^ORCID,Beffinger Michal Mateusz²^ORCID,Pantelyushin Stanislav²^ORCID,Linecker Michael¹^ORCID,Roth Lilian¹³,Lehmann Kuno³,Ungethüm Udo¹,Kobold Sebastian⁴⁵^ORCID,Graf Rolf¹^ORCID,van den Broek Maries⁶^ORCID,vom Berg Johannes²^ORCID,Gupta Anurag¹^ORCID,Clavien Pierre-Alain¹^ORCID

Affiliation:

1. Laboratory of the Swiss Hepato-Pancreatico-Biliary (HPB) and Transplantation Centre, Department of Surgery, University Hospital and University of Zürich, Raemistrasse 100, CH-8091 Zürich, Switzerland.

2. Institute of Laboratory Animal Science, University of Zürich, Wagistrasse 12, CH-8952 Schlieren, Switzerland.

3. Surgical Oncology Research Laboratory, Department of Surgery, University Hospital and University of Zürich, Raemistrasse 100, CH-8091 Zürich, Switzerland.

4. Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Klinikum der Ludwig-Maximilians-Universität München, Lindwurmstrasse 2a, D-80337 Munich, Germany.

5. German Center for Translational Cancer Research (DKTK), partner site Munich, Pettenkoferstr. 8a, D-80336 Munich, Germany.

6. Institute of Experimental Immunology, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.

Abstract

Serotonin dampens tumor-specific immunity in pancreatic and colorectal cancer mouse models.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference73 articles.

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3. Role of serotonin in the hepato-gastroIntestinal tract: an old molecule for new perspectives