Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy-Reference-Cited by-同舟云学术

Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy

Published:2019-06-26 Issue:498 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Momin Noor¹²^ORCID,Mehta Naveen K.¹²^ORCID,Bennett Nitasha R.¹^ORCID,Ma Leyuan¹³^ORCID,Palmeri Joseph R.¹⁴^ORCID,Chinn Magnolia M.¹²^ORCID,Lutz Emi A.¹²^ORCID,Kang Byong¹²^ORCID,Irvine Darrell J.¹²³⁵⁶^ORCID,Spranger Stefani¹⁷^ORCID,Wittrup K. Dane¹²⁴^ORCID

Affiliation:

1. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

3. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

4. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

5. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.

6. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

7. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

Abstract

Collagen-localized cytokines potentiate disparate systemic cancer immunotherapies while minimizing toxicity in many tumor models.

Funder

National Cancer Institute

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference62 articles.

1. Elements of cancer immunity and the cancer–immune set point

2. Phase I trial of subcutaneous recombinant human interleukin-2 in patients with metastatic melanoma

3. Pharmacokinetics and immunological aspects of a phase Ib study with intratumoral administration of recombinant human interleukin-12 in patients with head and neck squamous cell carcinoma: A decrease of T-bet in peripheral blood mononuclear cells;van Herpen C. M.;Clin. Cancer Res.,2003

4. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

5. Eradication of spontaneous malignancy by local immunotherapy

Cited by 136 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Engineering approaches for innate immune-mediated tumor microenvironment remodeling;Immuno-Oncology and Technology;2024-03

2. Engineering Anticytokine Antibodies for Immune Modulation;The Journal of Immunology;2024-01-15

3. Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity;2024-01-03

4. Electrostatic-driven Interactions Enhance Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies;2023-12-23

5. Mathematical modeling of intratumoral immunotherapy yields strategies to improve the treatment outcomes;PLOS Computational Biology;2023-12-19