Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T FH cells-Reference-Cited by-同舟云学术

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T FH cells

Published:2019-02-06 Issue:478 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Dan Jennifer M.¹²^ORCID,Havenar-Daughton Colin¹³^ORCID,Kendric Kayla¹,Al-kolla Rita¹,Kaushik Kirti¹,Rosales Sandy L.¹,Anderson Ericka L.⁴⁵⁶,LaRock Christopher N.⁴⁵⁷^ORCID,Vijayanand Pandurangan¹^ORCID,Seumois Grégory¹^ORCID,Layfield David⁸,Cutress Ramsey I.⁸,Ottensmeier Christian H.⁸^ORCID,Lindestam Arlehamn Cecilia S.¹^ORCID,Sette Alessandro¹²^ORCID,Nizet Victor⁴⁵^ORCID,Bothwell Marcella⁹¹⁰¹¹^ORCID,Brigger Matthew⁹¹⁰¹¹^ORCID,Crotty Shane¹²³^ORCID

Affiliation:

1. Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.

2. Department of Medicine, Division of Infectious Diseases, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.

3. Scripps Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID), La Jolla, CA 92037, USA.

4. Department of Pediatrics, School of Medicine, UCSD, La Jolla, CA 92037, USA.

5. Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA 92037, USA.

6. Human Longevity Inc., San Diego, CA 92121, USA.

7. Department of Microbiology and Immunology, Emory School of Medicine, Atlanta, GA 30322, USA.

8. Cancer Sciences Division, Faculty of Medicine, University of Southampton, UK.

9. Division of Pediatric Otolaryngology, Rady Children’s Hospital, San Diego, CA 92123, USA.

10. Department of Surgery, UCSD, La Jolla, CA 92037, USA.

11. Department of Otolaryngology, Head and Neck Surgery, Naval Medical Center San Diego, San Diego, CA 92134, USA.

Abstract

Recurrent tonsillitis is a multifactorial disease associated with an aberrant tonsillar germinal center response to group A Streptococcus .

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Thrasher Research Fund

Clinical Research Fellowship Grant UK

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference70 articles.

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