CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans-Reference-Cited by-同舟云学术

CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans

Published:2024-08-20 Issue:9 Volume:25 Page:1731-1741
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Borcherding Nicholas,Kim Wooseob^ORCID,Quinn Michael,Han Fangjie,Zhou Julian Q.^ORCID,Sturtz Alexandria J.,Schmitz Aaron J.,Lei Tingting,Schattgen Stefan A.^ORCID,Klebert Michael K.,Suessen Teresa,Middleton William D.,Goss Charles W.,Liu Chang,Crawford Jeremy Chase^ORCID,Thomas Paul G.^ORCID,Teefey Sharlene A.,Presti Rachel M.,O’Halloran Jane A.,Turner Jackson S.^ORCID,Ellebedy Ali H.^ORCID,Mudd Philip A.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Barnes Jewish Hospital Foundation

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41590-024-01888-9.pdf

Reference69 articles.

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2. Painter, M. M. et al. Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination. Immunity 54, 2133–2142 (2021).

3. Mudd, P. A. et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell 185, 603–613 (2022).

4. Crotty, S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621–663 (2011).

5. Vinuesa, C. G., Linterman, M. A., Yu, D. & MacLennan, I. C. M. Follicular helper T cells. Annu. Rev. Immunol. 34, 335–368 (2016).

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1. TFH cell responses endure in human lymph nodes after vaccination;Nature Immunology;2024-08-20