Reduction of intratumoral brain perfusion by noninvasive transcranial electrical stimulation

Author:

Sprugnoli G.1ORCID,Monti L.2,Lippa L.3ORCID,Neri F.1ORCID,Mencarelli L.1ORCID,Ruffini G.4ORCID,Salvador R.4ORCID,Oliveri G.3,Batani B.3,Momi D.1ORCID,Cerase A.2ORCID,Pascual-Leone A.56,Rossi A.17,Rossi S.17,Santarnecchi E.15ORCID

Affiliation:

1. Brain Investigation and Neuromodulation Laboratory, Department of Medicine, Surgery and Neuroscience, Unit of Neurology and Clinical Neurophysiology, Siena Medical School, Siena, Italy.

2. Unit of Neuroimaging and Neurointervention, “Santa Maria alle Scotte” Medical Center, Siena, Italy.

3. Unit of Neurosurgery, “Santa Maria alle Scotte” Medical Center, Siena, Italy.

4. Neuroelectrics, Barcelona, Spain.

5. Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Medical Center, Harvard Medical School, Boston, MA, USA.

6. Institut Guttmann, Universitat Autonoma Barcelona, Barcelona, Spain.

7. Department of Medicine, Surgery and Neuroscience, Human Physiology Section, Siena Medical School, Siena, Italy.

Abstract

Transcranial electrical stimulation can safely and noninvasively modulate perfusion of brain tumors in humans.

Funder

National Institutes of Health

Sidney R. Baer Jr. Foundation

Berenson-Allen Foundation

Harvard Clinical and Translational Science Center

Broad Institute

Defense Sciences Office, DARPA

Beth Israel Deaconess Medical Center

National Institute of Aging

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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5. Blood perfusion of subcutaneous tumours in mice following the application of low-level direct electric current;Jarm T.;Adv. Exp. Med. Biol.,1999

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