Enhancing Methotrexate Delivery in the Brain by Mesoporous Silica Nanoparticles Functionalized with Cell-Penetrating Peptide using <i>in Vivo</i> and <i>ex Vivo</i> Monitoring-Reference-Cited by-同舟云学术

Enhancing Methotrexate Delivery in the Brain by Mesoporous Silica Nanoparticles Functionalized with Cell-Penetrating Peptide using in Vivo and ex Vivo Monitoring

Published:2023-02-10 Issue:3 Volume:20 Page:1531-1548
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Shadmani Nasim¹²³,Makvandi Pooyan⁴^ORCID,Parsa Maliheh⁵⁶,Azadi Amir⁷⁸^ORCID,Nedaei Keivan⁹,Mozafari Negin⁷,Poursina Narges¹⁰,Mattoli Virgilio¹¹^ORCID,Tay Franklin R.¹²^ORCID,Maleki Aziz¹²,Hamidi Mehrdad¹²³¹³^ORCID

Affiliation:

1. Zanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

2. Department of Pharmaceutical Nanotechnology, School of Pharmacy, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

3. Trita Nanomedicine Research & Technology Development Center (TNRTC), Zanjan Health Technology Park, 45156-13191Zanjan, Iran

4. School of Engineering, Institute for Bioengineering, The University of Edinburgh, EdinburghEH9 3JL, U.K.

5. Department of Toxicology & Pharmacology, Faculty of Pharmacy, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

6. Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

7. Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, 71468 64685Shiraz, Iran

8. Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, 71468 64685Shiraz, Iran

9. Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

10. Department of Pharmaceutical Biomaterials, School of Pharmacy, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

11. Centre for Materials Interfaces, Istituto Italiano di Tecnologia, Viale Rinaldo Piaggio 34, 56025Pontedera, Pisa, Italy

12. The Graduate School, Augusta University, Augusta, Georgia30912, United States

13. Department of Pharmaceutics, School of Pharmacy, Zanjan University of Medical Sciences, 45139-56184Zanjan, Iran

Funder

Iran National Science Foundation

Zanjan Pharmaceutical Nanotechnology Research Center

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00755

Reference112 articles.

1. Drug Delivery to the Brain across the Blood-Brain Barrier Using Nanomaterials

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5. Enhancing Doxorubicin Delivery in Solid Tumor by Superhydrophobic Amorphous Calcium Carbonate–Doxorubicin Silica Nanoparticles with Focused Ultrasound

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