Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption
Author:
Affiliation:
1. Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
2. Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Abstract
Funder
National Institutes of Health
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference54 articles.
1. NPC1L1 and cholesterol transport
2. Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
3. Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport
4. Accumulation of Dietary Cholesterol in Sitosterolemia Caused by Mutations in Adjacent ABC Transporters
5. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
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