Experimental and theoretical explorations of nanocarriers’ multistep delivery performance for rational design and anticancer prediction

Author:

Bao Weier12ORCID,Tian Falin3ORCID,Lyu Chengliang2ORCID,Liu Bin1ORCID,Li Bin3ORCID,Zhang Luyao3,Liu Xianwu12,Li Feng2,Li Dan1,Gao Xiaoyong2ORCID,Wang Shuo2,Wei Wei24ORCID,Shi Xinghua34ORCID,Li Yuan1ORCID

Affiliation:

1. Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, P. R. China.

2. State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P. R. China.

3. Laboratory of Theoretical and Computational Nanoscience, Chinese Academy of Sciences (CAS) Key Laboratory for Nanosystem and Hierarchy Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, P. R. China.

4. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, P. R. China.

Abstract

An α-lactalbumin-based anticancer nanocarrier platform was designed for efficient rational design and potent in vivo prediction.

Funder

Beijing Nova Program

the National Key R&D Program of China

The financial supports from the National Natural Science Foundation of China

the Opening Fund of State Key Laboratory of Nonlinear Mechanics, and the China Postdoctoral Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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