Evaluating biological activity of compounds by transcription factor activity profiling-Reference-Cited by-同舟云学术

Evaluating biological activity of compounds by transcription factor activity profiling

Published:2018-09-07 Issue:9 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Medvedev Alexander¹^ORCID,Moeser Matt¹^ORCID,Medvedeva Liubov¹,Martsen Elena¹,Granick Alexander¹^ORCID,Raines Lydia¹,Zeng Ming¹,Makarov Sergei¹^ORCID,Houck Keith A.²^ORCID,Makarov Sergei S.¹^ORCID

Affiliation:

1. Attagene Inc., P.O. Box 12054, Research Triangle Park, NC 27709, USA.

2. U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, D343-03, Research Triangle Park, NC 27711, USA.

Abstract

Transcription factor activity profiling reveals invariant signatures of perturbed biological pathways and cell systems.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference65 articles.

1. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

2. Ontological analysis of gene expression data: Current tools, limitations, and open problems;Khatri P.;Bioinformatics,2005

3. Discovery of drug mode of action and drug repositioning from transcriptional responses

4. Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors;Romanov S.;Nat. Methods,2008

5. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA’s ToxCast program;Martin M. T.;Chem. Res. Toxicol.,2010

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