Phase transition specified by a binary code patterns the vertebrate eye cup

Author:

Balasubramanian Revathi1ORCID,Min Xuanyu1ORCID,Quinn Peter M. J.1ORCID,Giudice Quentin Lo2ORCID,Tao Chenqi1ORCID,Polanco Karina3,Makrides Neoklis1,Peregrin John1ORCID,Bouaziz Michael1ORCID,Mao Yingyu1,Wang Qian1ORCID,da Costa Bruna L.1ORCID,Buenaventura Diego4,Wang Fen5ORCID,Ma Liang6,Tsang Stephen H.1789,Fabre Pierre J.2ORCID,Zhang Xin17ORCID

Affiliation:

1. Department of Ophthalmology, Columbia University, New York, NY, USA.

2. Department of Basic Neurosciences, University of Geneva, Geneva, Switzerland.

3. Department of Psychology, Columbia University, New York, NY, USA.

4. Department of Biology, The City College of New York, New York, NY, USA.

5. Center for Cancer Biology and Nutrition, Institute of Biosciences and Technology, Texas A&M, Houston, TX, USA.

6. Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

7. Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

8. Jonas Children’s Vision Care, and Bernard and Shirley Brown Glaucoma Laboratory, Columbia Stem Cell Initiative, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.

9. Edward S. Harkness Eye Institute, New York Presbyterian Hospital, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.

Abstract

FGF and Wnt signaling controls the phase transition of the ocular fate.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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