Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state

Author:

Liu Haoming12ORCID,Du Yingying12ORCID,St-Pierre Jean-Philippe345,Bergholt Mads S.345,Autefage Hélène3456,Wang Jianglin12,Cai Mingle12,Yang Gaojie12,Stevens Molly M.345ORCID,Zhang Shengmin12ORCID

Affiliation:

1. Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China.

2. Advanced Biomaterials and Tissue Engineering Centre, Huazhong University of Science and Technology, Wuhan 430074, China.

3. Department of Materials, Imperial College London, London SW7 2AZ, UK.

4. Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.

5. Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.

6. Division of Biomaterials, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

Abstract

We report a biodegradable synthetic material that opens a door to repair damaged tissue via boosting cellular energy metabolism.

Funder

National Natural Science Foundation of China

the National Key R & D Project

the UK Regenerative Medicine Platform

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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