Thermosensitive receptors in neural stem cells link stress-induced hyperthermia to impaired neurogenesis via microglial engulfment

Author:

Hoshi Yutaka1ORCID,Shibasaki Koji2ORCID,Gailly Philippe3ORCID,Ikegaya Yuji145ORCID,Koyama Ryuta1ORCID

Affiliation:

1. Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.

2. Laboratory of Neurochemistry, Graduate School of Human Health Science, University of Nagasaki, Nagasaki 851-2195, Japan.

3. Laboratory of Cell Physiology, Institute of Neuroscience, Université catholique de Louvain, B-1200 Brussels, Belgium.

4. Institute for AI and Beyond, The University of Tokyo, Tokyo 113-0033, Japan.

5. Center for Information and Neural Networks, National Institute of Information and Communications Technology, Suita City, Osaka 565-0871, Japan.

Abstract

Hyperthermia mediates social defeat stress–induced impairment of adult neurogenesis.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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