E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation-Reference-Cited by-同舟云学术

E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation

Published:2021-05-07 Issue:19 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Duan Jie-Lin¹^ORCID,He Hui-Qian¹,Yu Yao¹^ORCID,Liu Tao¹,Ma Shu-Jun²^ORCID,Li Fan¹^ORCID,Jiang Yan-Shan¹^ORCID,Lin Xin³^ORCID,Li De-Dong¹,Lv Quan-Zhen¹^ORCID,Ma Hui-Hui¹,Jia Xin-Ming¹^ORCID

Affiliation:

1. Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai 200092, China

2. Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

3. Institute for Immunology, Tsinghua University School of Medicine, Tsinghua University-Peking University Jointed Center for Life Sciences, Beijing 100084, China.

Abstract

c-Cbl suppresses RelB activation to facilitate protective benefits of commensal fungi and maintain intestinal homeostasis.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Science and Technology Innovation Plan Of Shanghai Science and Technology Commission

Innovation Program of Shanghai Municipal Education Commission

Shanghai Municipal Natural Science Foundation

Innovative research team of high-level local universities in Shanghai

Outstanding academic leader program of Shanghai health and Family Planning Commission

Shuguang Program of Shanghai Municipal Education Commission

Publisher