Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation-Reference-Cited by-同舟云学术

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Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation

Published:2020-04-03 Issue:14 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Sharma Nandini¹^ORCID,Ahalawat Navjeet²^ORCID,Sandhu Padmani¹,Strauss Erick³^ORCID,Mondal Jagannath²,Anand Ruchi¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India.

2. Center for Interdisciplinary Science, Tata Institute of Fundamental Research, Hyderabad 500107, India.

3. Department of Biochemistry, Stellenbosch University, Stellenbosch 7602, South Africa.

Abstract

Transfer of labile intermediate in bifunctional enzymes occurs via transient molecular tunnels controlled by allosteric signals.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference57 articles.

1. Allosteric Mechanisms of Signal Transduction

2. Is allostery an intrinsic property of all dynamic proteins?

3. Allosteric regulation and catalysis emerge via a common route

4. Dynamic personalities of proteins

5. Conformational changes: How small is big enough?

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