Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

Author:

Kildisiute Gerda1ORCID,Kholosy Waleed M.2ORCID,Young Matthew D.1ORCID,Roberts Kenny1ORCID,Elmentaite Rasa1ORCID,van Hooff Sander R.2,Pacyna Clarissa N.1ORCID,Khabirova Eleonora1,Piapi Alice3,Thevanesan Christine3ORCID,Bugallo-Blanco Eva3ORCID,Burke Christina3ORCID,Mamanova Lira1ORCID,Keller Kaylee M.2,Langenberg-Ververgaert Karin P.S.2ORCID,Lijnzaad Philip2ORCID,Margaritis Thanasis2ORCID,Holstege Frank C.P.2ORCID,Tas Michelle L.2ORCID,Wijnen Marc H.W.A.2,van Noesel Max M.2,del Valle Ignacio3ORCID,Barone Giuseppe4ORCID,van der Linden Reinier5ORCID,Duncan Catriona4ORCID,Anderson John34ORCID,Achermann John C.3ORCID,Haniffa Muzlifah167ORCID,Teichmann Sarah A.1ORCID,Rampling Dyanne4ORCID,Sebire Neil J.4ORCID,He Xiaoling89,de Krijger Ronald R.210,Barker Roger A.89ORCID,Meyer Kerstin B.1ORCID,Bayraktar Omer1,Straathof Karin34ORCID,Molenaar Jan J.2ORCID,Behjati Sam11112ORCID

Affiliation:

1. Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

2. Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

3. UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

4. Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

5. Hubrecht Institute, KNAW, 3584 CT Utrecht, Netherlands.

6. Institute of Cellular Medicine, Newcastle University, NE2 4HH Newcastle upon Tyne, UK.

7. Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals, NHS Foundation Trust, NE2 4LP Newcastle upon Tyne, UK.

8. MRC-WT Cambridge Stem Cell Institute, University of Cambridge, CB2 0QQ Cambridge, UK.

9. Department of Clinical Neurosciences, University of Cambridge, CB2 0QQ Cambridge, UK.

10. Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.

11. Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.

12. Department of Paediatrics, University of Cambridge, CB2 0QQ Cambridge, UK.

Abstract

Comparisons of neuroblastoma cells and relevant normal adrenal cells reveal a uniform cell state that characterizes neuroblastoma.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference58 articles.

1. Neuroblastoma

2. Schwann cell precursor: a neural crest cell in disguise?

3. The natural history of neuroblastic cells in the fetal adrenal gland;Turkel S. B.;Am. J. Pathol.,1974

4. Neuroblastoma stage 4S: a multifocal stem-cell disease of the developing neural crest

Cited by 98 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3