Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation

Author:

Kunz Lukas1ORCID,Wang Liang234,Lachner-Piza Daniel1ORCID,Zhang Hui5,Brandt Armin1ORCID,Dümpelmann Matthias1ORCID,Reinacher Peter C.6ORCID,Coenen Volker A.6,Chen Dong7,Wang Wen-Xu7,Zhou Wenjing8ORCID,Liang Shuli9,Grewe Philip10,Bien Christian G.10,Bierbrauer Anne5ORCID,Navarro Schröder Tobias11ORCID,Schulze-Bonhage Andreas1ORCID,Axmacher Nikolai5ORCID

Affiliation:

1. Epilepsy Center, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.

2. CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.

3. CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai, China.

4. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.

5. Department of Neuropsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr University Bochum, Bochum, Germany.

6. University Medical Center, Stereotactic and Functional Neurosurgery, Freiburg im Breisgau, Germany.

7. School of Systems Science, Beijing Normal University, Beijing, China.

8. Department of Epilepsy Center, Tsinghua University Yuquan Hospital, Beijing, China.

9. Department of Neurosurgery, First Affiliated Hospital of General Hospital of PLA, Beijing, China.

10. Bethel Epilepsy Centre, Krankenhaus Mara, Bielefeld, Germany.

11. Kavli Institute for Systems Neuroscience, Centre for Neural Computation, The Egil and Pauline Braathen and Fred Kavli Centre for Cortical Microcircuits, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

Abstract

Hippocampal theta cycles provide a means to maintain and segregate different goal representations during human wayfinding.

Funder

National Science Foundation

National Institutes of Health

Deutsche Forschungsgemeinschaft

Chinese Academy of Sciences

National Natural Science Foundation of China

Beijing Municipal Science and Technology Commission

Bundesministerium für Bildung und Forschung

German Ministry for Economic Affairs and Energy

Medical Faculty of the University of Freiburg

Else Kröner-Fresenius-Stiftung

von Bodelschwingh Foundation Bethel

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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