A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons-Reference-Cited by-同舟云学术

A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Published:2018-09-07 Issue:9 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Kozlenkov Alexey¹²^ORCID,Li Junhao³^ORCID,Apontes Pasha¹,Hurd Yasmin L.²,Byne William M.¹²,Koonin Eugene V.⁴^ORCID,Wegner Michael⁵^ORCID,Mukamel Eran A.³^ORCID,Dracheva Stella¹²^ORCID

Affiliation:

1. James J. Peters VA Medical Center, Bronx, NY 10468, USA.

2. Friedman Brain Institute and Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

3. Department of Cognitive Science, University of California, San Diego, San Diego, CA 92037, USA.

4. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

5. Institut für Biochemie, Emil-Fischer-Zentrum, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen 91054, Germany.

Abstract

DNA hydroxymethylation is a distinctive epigenetic regulator of human inhibitory neurons, potentially affecting brain diseases.

Funder

National Institute of Mental Health

National Institute on Drug Abuse

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference61 articles.

1. Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

2. DNA methylation: roles in mammalian development

3. Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington’s canal;Hemberger M.;Nat. Rev. Mol. Cell Biol.,2009

4. Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

5. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

Cited by 98 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Review article: the role of epigenetics as an underlying regulator of the immune responses in Parkinson’s disease;Epigenetics Reports;2024-09-10

2. Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers;Cell Death & Disease;2024-08-25

3. Cell-type-specific effects of age and sex on human cortical neurons;Neuron;2024-08

4. Decoding the Epigenetic Landscape: Insights into 5mC and 5hmC Patterns in Mouse Cortical Cell Types;2024-07-10

5. Unraveling the Epigenetic Landscape: Insights into Parkinson’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis;Brain Sciences;2024-05-29