Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep-Reference-Cited by-同舟云学术

Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep

Published:2020-04-10 Issue:15 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Hayat Hanna¹^ORCID,Regev Noa¹,Matosevich Noa²,Sales Anna³^ORCID,Paredes-Rodriguez Elena³⁴⁵^ORCID,Krom Aaron J.¹⁶^ORCID,Bergman Lottem¹^ORCID,Li Yong³,Lavigne Marina⁷^ORCID,Kremer Eric J.⁷^ORCID,Yizhar Ofer⁸^ORCID,Pickering Anthony E.³⁹,Nir Yuval¹²¹⁰^ORCID

Affiliation:

1. Department Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

2. Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.

3. School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK.

4. Department of Pharmacology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.

5. Neurodegenerative Diseases Group, Biocruces-Bizkaia Health Research Institute, 48903 Barakaldo, Spain.

6. Department of Anesthesiology and Critical Care Medicine, Hadassah-Hebrew University Medical Center, Hebrew University–Hadassah School of Medicine, Jerusalem, Israel.

7. Institute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.

8. Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.

9. Department of Anaesthesia, University Hospitals Bristol, Bristol BS2 8HW, UK.

10. Functional Neurophysiology and Sleep Research Laboratory, Tel-Aviv Sourasky Medical Center, Tel Aviv 64239, Israel.

Abstract

Do noises wake you up at night? Blame your locus coeruleus.

Funder

European Research Council

Israel Science Foundation

Centre National de la Recherche Scientifique

European Society of Anaesthesiology

Adelis Foundation