Glucagon regulates the stability of REV-ERBα to modulate hepatic glucose production in a model of lung cancer–associated cachexia

Author:

Verlande Amandine1ORCID,Chun Sung Kook1,Goodson Maggie O.1ORCID,Fortin Bridget M.1ORCID,Bae Hosung1ORCID,Jang Cholsoon1ORCID,Masri Selma1ORCID

Affiliation:

1. Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.

Abstract

Glucagon signaling governs REV-ERBα stability to modulate hepatic glucose production in a model of lung cancer cachexia.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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