The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing-Reference-Cited by-同舟云学术

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The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing

Published:2021-07-30 Issue:31 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Jin Seung-Gi¹^ORCID,Pettinga Dean²^ORCID,Johnson Jennifer¹,Li Peipei³^ORCID,Pfeifer Gerd P.¹^ORCID

Affiliation:

1. Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.

2. Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI 49503, USA.

3. Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI 49503, USA.

Abstract

The sequence specificity of pyrimidine dimers with deaminated cytosines is highly similar to that of mutations in melanoma.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference57 articles.

1. Signatures of mutational processes in human cancer

2. Cancer Genome Landscapes

3. Mechanisms underlying mutational signatures in human cancers

4. Somatic mutation in cancer and normal cells

5. How the environment shapes cancer genomes

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Methods and applications of genome-wide profiling of DNA damage and rare mutations;Nature Reviews Genetics;2024-06-25

2. The Surprising Diversity of UV‐Induced Mutations;Advanced Genetics;2024-03-07

3. High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma;Proceedings of the National Academy of Sciences;2024-01-19

4. The accurate bypass of pyrimidine dimers by DNA polymerase eta contributes to ultraviolet-induced mutagenesis;Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis;2024-01

5. Analysis of cytosine deamination events in excision repair sequencing reads reveals mechanisms of incision site selection in NER;Nucleic Acids Research;2023-12-18

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