Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle-Reference-Cited by-同舟云学术

Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle

Published:2020-11-13 Issue:46 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Kiss Balázs¹^ORCID,Gohlke Jochen¹^ORCID,Tonino Paola¹^ORCID,Hourani Zaynab¹,Kolb Justin¹^ORCID,Strom Joshua¹^ORCID,Alekhina Olga¹^ORCID,Smith John E.¹^ORCID,Ottenheijm Coen¹,Gregorio Carol¹^ORCID,Granzier Henk¹²^ORCID

Affiliation:

1. Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85721, USA.

2. Allan and Alfie Endowed Chair for Heart Disease in Women Research, Sarver Molecular Cardiovascular Research Program, University of Arizona, Tucson, AZ 85721, USA.

Abstract

Nebulin rules thin-filament length in fast skeletal muscle but collaborates with leiomodin-2 in muscles optimized for efficiency.

Funder

National Heart, Lung, and Blood Institute

National Institute of Arthritis and Musculoskeletal and Skin Diseases

A Foundation Building Strength

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference47 articles.

1. Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency