Disruption of cardiac thin filament assembly arising from a mutation in LMOD2 : A novel mechanism of neonatal dilated cardiomyopathy-Reference-Cited by-同舟云学术

Disruption of cardiac thin filament assembly arising from a mutation in LMOD2 : A novel mechanism of neonatal dilated cardiomyopathy

Published:2019-09-06 Issue:9 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Ahrens-Nicklas Rebecca C.¹^ORCID,Pappas Christopher T.²^ORCID,Farman Gerrie P.²,Mayfield Rachel M.²^ORCID,Larrinaga Tania M.²^ORCID,Medne Livija¹,Ritter Alyssa¹,Krantz Ian D.¹,Murali Chaya¹^ORCID,Lin Kimberly Y.³^ORCID,Berger Justin H.³^ORCID,Yum Sabrina W.⁴,Carreon Chrystalle Katte⁵,Gregorio Carol C.²^ORCID

Affiliation:

1. Division of Human Genetics, The Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

2. Department of Cellular and Molecular Medicine and Sarver Molecular Cardiovascular Research Program, The University of Arizona, Tucson, AZ, USA.

3. Division of Pediatric Cardiology, The Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

4. Division of Pediatric Neurology, The Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

5. Department of Pathology, The Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Abstract

Similarities between a mouse model and human patient informed diagnosis and management of a novel cause of dilated cardiomyopathy.

Funder

National Institutes of Health

National Heart, Lung, and Blood Institute

National Institute of General Medical Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference35 articles.

1. Dilated cardiomyopathy: the complexity of a diverse genetic architecture