Tissue-specific genetic features inform prediction of drug side effects in clinical trials-Reference-Cited by-同舟云学术

Tissue-specific genetic features inform prediction of drug side effects in clinical trials

Published:2020-09-11 Issue:37 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Duffy Áine¹²^ORCID,Verbanck Marie¹²³^ORCID,Dobbyn Amanda¹²⁴^ORCID,Won Hong-Hee⁵^ORCID,Rein Joshua L.⁶,Forrest Iain S.¹²^ORCID,Nadkarni Girish²⁶,Rocheleau Ghislain¹²,Do Ron¹²^ORCID

Affiliation:

1. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

2. Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

3. Université de Paris, UR 7537 BioSTM, Paris, France.

4. Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

5. Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, South Korea.

6. Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Abstract

Tissue-specific genetic features in multiple tissues can inform prediction of drug side effects in clinical trials.

Funder

National Institutes of Health

National Research Foundation of Korea

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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