Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc-Reference-Cited by-同舟云学术

Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc

Author:

Hernandez Paula A.¹^ORCID,Jacobsen Timothy D.²^ORCID,Chahine Nadeen O.²³^ORCID

Affiliation:

1. Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

2. Department of Biomedical Engineering, Columbia University, New York, NY, USA.

3. Department of Orthopedic Surgery, Columbia University, New York, NY, USA.

Abstract

Rho Rho Rho your cells: Increased RhoA activity protects intervertebral disc from TNFα-induced degradation.

Funder

National Science Foundation

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

4. Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues;Shamji M. F.;Arthritis Rheum.,2010

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