Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation-Reference-Cited by-同舟云学术

Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation

Published:2021-11-19 Issue:47 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Oda Yukako¹^ORCID,Takahashi Chisato²³^ORCID,Harada Shota⁴^ORCID,Nakamura Shun⁵⁶^ORCID,Sun Daxiao⁷,Kiso Kazumi¹^ORCID,Urata Yuko¹^ORCID,Miyachi Hitoshi⁸^ORCID,Fujiyoshi Yoshinori⁵⁶^ORCID,Honigmann Alf⁷^ORCID,Uchida Seiichi⁴^ORCID,Ishihama Yasushi²^ORCID,Toyoshima Fumiko¹^ORCID

Affiliation:

1. Department of Biosystems Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.

2. Department of Molecular and Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.

3. Laboratory of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyoto 610-0395, Japan.

4. Laboratory of Human Interface, Graduate School of Systems Life Sciences, Kyushu University, Fukuoka 819-0395, Japan.

5. Cellular and Structural Physiology Laboratory, Advanced Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.

6. CeSPIA Inc., Tokyo 100-0004, Japan.

7. Max Planck Institute of Molecular Cell Biology and Genetics, Dresden 01309, Germany.

8. Reproductive Engineering Team, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.

Abstract

C-terminal alpha 1-antitrypsin peptides induce tight junction formation by activating G protein G13.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference54 articles.

1. Physiology and Function of the Tight Junction

2. Claudin-related intestinal diseases

3. Inflammation and the Intestinal Barrier: Leukocyte–Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair

4. Multifunctional strands in tight junctions

5. Intestinal mucosal barrier function in health and disease

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