The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output-Reference-Cited by-同舟云学术

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output

Published:2021-08-06 Issue:32 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Kanellis Dimitris C.¹^ORCID,Espinoza Jaime A.¹^ORCID,Zisi Asimina¹^ORCID,Sakkas Elpidoforos²,Bartkova Jirina¹³,Katsori Anna-Maria¹⁴,Boström Johan⁵^ORCID,Dyrskjøt Lars⁶,Broholm Helle⁷^ORCID,Altun Mikael⁵^ORCID,Elsässer Simon J.¹⁴^ORCID,Lindström Mikael S.¹^ORCID,Bartek Jiri¹³^ORCID

Affiliation:

1. Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 21 Stockholm, Sweden.

2. Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.

3. Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.

4. Ming Wai Lau Centre for Reparative Medicine, Stockholm Node, Karolinska Institutet, Stockholm 17165, Sweden.

5. Science for Life Laboratory, Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, SE-141 52 Huddinge, Sweden.

6. Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.

7. Department of Pathology, Copenhagen University Hospital, Copenhagen, Denmark.

Abstract

The exon junction complex helicase eIF4A3 orchestrates Pol I and Pol II posttranscriptional events.

Funder

Cancerfonden

Vetenskapsrådet

NCBI BioProject

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary