Salmonella Typhi Vi capsule prime-boost vaccination induces convergent and functional antibody responses

Author:

Dahora Lindsay C.12ORCID,Verheul Marije K.3,Williams Katherine L.4,Jin Celina3,Stockdale Lisa3ORCID,Cavet Guy4,Giladi Eldar4ORCID,Hill Jennifer3,Kim Dongkyoon4,Leung Yvonne4,Bobay Benjamin G.567ORCID,Spicer Leonard D.567,Sawant Sheetal18ORCID,Rijpkema Sjoerd9ORCID,Dennison S. Moses18ORCID,Alam S. Munir101112ORCID,Pollard Andrew J.3ORCID,Tomaras Georgia D.12813ORCID

Affiliation:

1. Center for Human Systems Immunology, Duke University, Durham, NC, USA.

2. Department of Immunology, Duke University, Durham, NC, USA.

3. Oxford Vaccine Group, Department of Pediatrics, University of Oxford and NIHR Oxford Biomedical Research Center, Oxford, UK.

4. Atreca Inc., San Carlos, CA, USA.

5. Department of Biochemistry, Duke University, Durham, NC, USA.

6. Department of Radiology, Duke University, Durham, NC, USA.

7. Duke University NMR Center, Duke University Medical Center, Durham, NC, USA.

8. Department of Surgery, Duke University, Durham, NC, USA.

9. Division of Bacteriology, National Institute of Biological Standards and Control, Potters Bar, UK.

10. Department of Medicine, Duke University, Durham, NC, USA.

11. Department of Pathology, Duke University, Durham, NC, USA.

12. Duke Human Vaccine Institute, Duke University, Durham, NC, USA.

13. Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.

Abstract

Prime-boost vaccination with S. Typhi Vi capsule induces convergent antibodies whose function depends on specificity and avidity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3