Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity-Reference-Cited by-同舟云学术

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Published:2019-06-07 Issue:36 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Snyder Annelise G.¹^ORCID,Hubbard Nicholas W.¹^ORCID,Messmer Michelle N.¹^ORCID,Kofman Sigal B.¹^ORCID,Hagan Cassidy E.¹,Orozco Susana L.¹²^ORCID,Chiang Kristy²^ORCID,Daniels Brian P.³,Baker David⁴^ORCID,Oberst Andrew¹^ORCID

Affiliation:

1. Department of Immunology, University of Washington, Seattle, WA 98109, USA.

2. Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98109, USA.

3. Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.

4. Institute for Protein Design, University of Washington, Seattle, WA 98109, USA.

Abstract

Activation of the necroptotic kinases RIPK1 and RIPK3 within the tumor microenvironment enhances immune-mediated tumor control.

Funder

National Cancer Institute

Cancer Research Institute

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference55 articles.

1. Radiotherapy and immune checkpoint blockade: potential interactions and future directions

2. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

3. Comparing the effects of different cell death programs in tumor progression and immunotherapy

4. Dying cells actively regulate adaptive immune responses

5. Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection

Cited by 273 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation;International Immunopharmacology;2024-12

2. Identification and validation of a five-necroptosis-related lncRNAs signature for prognostic prediction in hepatocellular carcinoma;Heliyon;2024-09

3. Nanomedicine-induced programmed cell death in cancer therapy: mechanisms and perspectives;Cell Death Discovery;2024-08-29

4. Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation;Nature Immunology;2024-08-21

5. Comprehensive expression, prognostic and validation analysis of necroptosis-related lncRNAs in esophageal cancer;Translational Oncology;2024-08