The promise of priming precursors: Advances in inducing CD4 binding site–directed HIV broadly neutralizing antibodies-Reference-Cited by-同舟云学术

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The promise of priming precursors: Advances in inducing CD4 binding site–directed HIV broadly neutralizing antibodies

Published:2024-08-30 Issue:98 Volume:9 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Amara Rama Rao¹²^ORCID

Affiliation:

1. Emory Vaccine Center, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA.

2. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30329, USA.

Abstract

HIV envelope immunogen designed to activate germline B cell precursors of CD4 binding site–specific neutralizing antibodies shows promise in monkeys.

Publisher

American Association for the Advancement of Science (AAAS)

Link

https://www.science.org/doi/pdf/10.1126/sciimmunol.adq8862

Reference6 articles.

1. Strategies for a multi-stage neutralizing antibody-based HIV vaccine

2. Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site

3. Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques

4. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

5. Early development of broadly neutralizing antibodies in HIV-1–infected infants

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. HIV: how close are we to a vaccine — or a cure?;Nature;2024-09-02

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