Genome-Wide RNAi Screen Reveals Disease-Associated Genes That Are Common to Hedgehog and Wnt Signaling-Reference-Cited by-同舟云学术

Genome-Wide RNAi Screen Reveals Disease-Associated Genes That Are Common to Hedgehog and Wnt Signaling

Author:

Jacob Leni S.¹,Wu Xiaofeng²,Dodge Michael E.¹,Fan Chih-Wei¹,Kulak Ozlem¹,Chen Baozhi¹,Tang Wei¹,Wang Baolin²³,Amatruda James F.⁴⁵,Lum Lawrence¹

Affiliation:

1. Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

2. Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.

3. Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

4. Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

5. Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Abstract

Loss of the kinase and tumor suppressor Stk11 (Lkb1) has opposite effects on Hh and Wnt signaling.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference43 articles.

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