A VASP-Rac–Soluble Guanylyl Cyclase Pathway Controls cGMP Production in Adipocytes

Author:

Jennissen Katja1,Siegel Franziska1,Liebig-Gonglach Michaela1,Hermann Michaela-Rosemarie12,Kipschull Stefanie1,van Dooren Sander1,Kunz Wolfram S.3,Fässler Reinhard2,Pfeifer Alexander14

Affiliation:

1. Institute of Pharmacology and Toxicology, University of Bonn, 53105 Bonn, Germany.

2. Department of Molecular Medicine, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

3. Division of Neurochemistry, Department of Epileptology, University of Bonn, 53105 Bonn, Germany.

4. Pharma-Center, University of Bonn, 53105 Bonn, Germany.

Abstract

Targeting the cGMP effector VASP may enhance metabolism by stimulating the activity and abundance of brown adipocytes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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