A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses-Reference-Cited by-同舟云学术

A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses

Published:2020-12-08 Issue:661 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Rommereim Leah M.¹^ORCID,Akhade Ajay Suresh¹^ORCID,Dutta Bhaskar²^ORCID,Hutcheon Carolyn¹^ORCID,Lounsbury Nicolas W.²^ORCID,Rostomily Clifford C.¹^ORCID,Savan Ram³^ORCID,Fraser Iain D. C.²^ORCID,Germain Ronald N.²^ORCID,Subramanian Naeha¹³⁴^ORCID

Affiliation:

1. Institute for Systems Biology, Seattle, WA 98109, USA.

2. Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0421, USA.

3. Department of Immunology, University of Washington, Seattle, WA 98109, USA.

4. Department of Global Health, University of Washington, Seattle, WA 98109, USA.

Abstract

A disproportionately large response is induced by small increases in the abundance of a pathogen sensor.

Funder

National Institutes of Health

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference46 articles.