Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition-Reference-Cited by-同舟云学术

Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition

Published:2015-05-12 Issue:376 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Xie Yi¹,Jin Yu¹,Merenick Bethany L.²³,Ding Min¹²³,Fetalvero Kristina M.²³,Wagner Robert J.³,Mai Alice³,Gleim Scott¹,Tucker David F.⁴,Birnbaum Morris J.⁴,Ballif Bryan A.⁵,Luciano Amelia K.¹,Sessa William C.¹,Rzucidlo Eva M.³,Powell Richard J.³,Hou Lin⁶,Zhao Hongyu⁶,Hwa John¹²,Yu Jun¹,Martin Kathleen A.¹²³

Affiliation:

1. Yale Cardiovascular Research Center, Vascular Biology and Therapeutics Program, and Departments of Medicine and Pharmacology, Yale University School of Medicine, New Haven, CT 06511, USA.

2. Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.

3. Department of Surgery, Section of Vascular Surgery, The Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.

4. Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

5. Department of Biology, University of Vermont, Burlington, VT 05405, USA.

6. Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.

Abstract

Increasing the activity of the transcription factor GATA-6 prevents excessive proliferation of vascular smooth muscle cells in injured blood vessels.

Funder

NIH National Heart, Lung, and Blood Institute

American Heart Association

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. Programming Smooth Muscle Plasticity With Chromatin Dynamics

2. Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease

3. Short- and Long-Term Outcomes With Drug-Eluting and Bare-Metal Coronary Stents

4. Molecular mechanisms of mTOR-mediated translational control

5. mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Restoration of ARA metabolic disorders in vascular smooth muscle cells alleviates intimal hyperplasia;European Journal of Pharmacology;2024-09

2. (Homo-)harringtonine prevents endothelial inflammation through IRF-1 dependent downregulation of VCAM1 mRNA expression and inhibition of cell adhesion molecule protein biosynthesis;Biomedicine & Pharmacotherapy;2024-07

3. Diabetes-Induced Vascular Dysfunction and Stemness Decline Investigated via Transcription Factor-Driven Genetic Switches;2024-05-30

4. Epigenetic Remodeling in Human Coronary Artery Smooth Muscle Cell Phenotypic Switching;2024-04-14

5. The transcription factor GATA6 accelerates vascular smooth muscle cell senescence-related arterial calcification by counteracting the role of anti-aging factor SIRT6 and impeding DNA damage repair;Kidney International;2024-01