Engineered chemotaxis core signaling units indicate a constrained kinase-off state-Reference-Cited by-同舟云学术

Engineered chemotaxis core signaling units indicate a constrained kinase-off state

Published:2020-11-10 Issue:657 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Muok Alise R.¹²^ORCID,Chua Teck Khiang¹^ORCID,Srivastava Madhur¹³^ORCID,Yang Wen²,Maschmann Zach¹^ORCID,Borbat Petr P.¹³,Chong Jenna¹^ORCID,Zhang Sheng¹^ORCID,Freed Jack H.¹³^ORCID,Briegel Ariane²^ORCID,Crane Brian R.¹^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

2. Institute for Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.

3. National Biomedical Center for Advanced ESR Technologies (ACERT), Cornell University, Ithaca, NY 14853, USA.

Abstract

Bacterial chemoreceptors keep the kinase CheA inactive by locking down its catalytic core.

Funder

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference76 articles.

1. Regulation of the chemotaxis histidine kinase CheA: A structural perspective

2. Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update

3. Architecture and signal transduction mechanism of the bacterial chemosensory array: Progress, controversies, and challenges

4. Bacterial chemoreceptors: providing enhanced features to two-component signaling

5. Quantitative modeling of sensitivity in bacterial chemotaxis: The role of coupling among different chemoreceptor species

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