MLK3 Is Part of a Feedback Mechanism That Regulates Different Cellular Responses to Reactive Oxygen Species-Reference-Cited by-同舟云学术

MLK3 Is Part of a Feedback Mechanism That Regulates Different Cellular Responses to Reactive Oxygen Species

Published:2014-06-03 Issue:328 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Lee Ho-Sung¹²,Hwang Chae Young¹³,Shin Sung-Young¹,Kwon Ki-Sun³,Cho Kwang-Hyun¹²

Affiliation:

1. Laboratory for Systems Biology and Bio-Inspired Engineering, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.

2. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.

3. Laboratory of Cell Signaling, Aging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.

Abstract

Computational analysis of signaling networks reveals how cells can choose between proliferation and death in response to oxidative stress.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference141 articles.

1. Reactive oxygen species in cell signaling

2. Oxidant Signaling in Vascular Cell Growth, Death, and Survival

3. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

4. Hydrogen Peroxide Sensing and Signaling

5. Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity

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