Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3 + Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms-Reference-Cited by-同舟云学术

Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3 + Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms

Published:2012-06-19 Issue:229 Volume:5 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Beier Ulf H.¹²,Wang Liqing³,Han Rongxiang³,Akimova Tatiana³,Liu Yujie³,Hancock Wayne W.²³

Affiliation:

1. Division of Nephrology, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.

2. University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

3. Division of Transplant Immunology, Department of Pathology and Laboratory Medicine and Biesecker Center for Pediatric Liver Disease, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Abstract

Combined inhibition of distinct histone deacetylases enhances the suppressive effects of regulatory T cells.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference35 articles.

1. Calcineurin Inhibitor Nephrotoxicity

2. Infection in Solid-Organ Transplant Recipients

3. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

4. Moving to tolerance: Clinical application of T regulatory cells

5. Control of Regulatory T Cell Development by the Transcription Factor Foxp3

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