Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity-Reference-Cited by-同舟云学术

Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity

Published:2016-07 Issue:7 Volume:2 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Yen Chi-Fu¹^ORCID,Harischandra Dilshan S.²,Kanthasamy Anumantha²,Sivasankar Sanjeevi¹³

Affiliation:

1. Department of Electrical and Computer Engineering, Iowa State University, Ames, IA 50011, USA.

2. Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.

3. Department of Physics and Astronomy, Iowa State University, Ames, IA 50011, USA.

Abstract

Copper induces prion protein misfolding, aggregation, and neurotoxicity.

Funder

National Institute of Environmental Health Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference78 articles.

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4. NMR solution structure of the human prion protein

5. NMR structure of the bovine prion protein isolated from healthy calf brains;Hornemann S.;EMBO Rep.,2004

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