Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier-Reference-Cited by-同舟云学术

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

Published:2015-09-04 Issue:8 Volume:1 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Keaney James¹,Walsh Dominic M.²^ORCID,O’Malley Tiernan²^ORCID,Hudson Natalie¹,Crosbie Darragh E.¹,Loftus Teresa³,Sheehan Florike³,McDaid Jacqueline¹,Humphries Marian M.¹,Callanan John J.⁴⁵,Brett Francesca M.³,Farrell Michael A.³,Humphries Peter¹,Campbell Matthew¹

Affiliation:

1. Smurfit Institute of Genetics, Lincoln Place Gate, Trinity College Dublin, Dublin 2, Ireland.

2. Laboratory for Neurodegenerative Research, Center for Neurological Diseases, Brigham and Women’s Hospital, Harvard Institute of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

3. Department of Neuropathology, Beaumont Hospital, Dublin 9, Ireland.

4. UCD School of Veterinary Medicine and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.

5. Ross University School of Veterinary Medicine, P. O. Box 334, Basseterre, St. Kitts, West Indies.

Abstract

Size-selective and passive paracellular diffusion of amyloid-β across tight junctions of the blood-brain barrier in Alzheimer’s disease.

Funder

Science Foundation Ireland

National Institutes of Health

BrightFocus Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference31 articles.