Bacterial antisense RNAs are mainly the product of transcriptional noise-Reference-Cited by-同舟云学术

Bacterial antisense RNAs are mainly the product of transcriptional noise

Published:2016-03-04 Issue:3 Volume:2 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Lloréns-Rico Verónica¹²,Cano Jaime¹²^ORCID,Kamminga Tjerko³⁴,Gil Rosario⁵^ORCID,Latorre Amparo⁵⁶^ORCID,Chen Wei-Hua⁷,Bork Peer⁷⁸,Glass John I.⁹¹⁰^ORCID,Serrano Luis¹²¹¹,Lluch-Senar Maria¹²

Affiliation:

1. EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain.

2. Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain.

3. MSD Animal Health, Bioprocess Technology and Support, 5830 AB Boxmeer, Netherlands.

4. Laboratory of Systems and Synthetic Biology, Wageningen University, 6700 EJ Wageningen, Netherlands.

5. Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, 46980 Paterna, València, Spain.

6. Área de Genómica y Salud, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)—Salud Pública, 46020 Valencia, Spain.

7. European Molecular Biology Laboratory, 69117 Heidelberg, Germany.

8. Max Delbrück Centre (MDC) for Molecular Medicine, 13125 Berlin, Germany.

9. Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, CA 92037, USA.

10. Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, Rockville, MD 20850, USA.

11. Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluis Companys 23, 08010 Barcelona, Spain.

Abstract

Most of the antisense transcripts in bacteria are the product of transcriptional noise derived from spurious promoters.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference67 articles.

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4. Pervasive transcription: Illuminating the dark matter of bacterial transcriptomes;Wade J. T.;Nat. Rev. Microbiol.,2014

5. Antisense transcription is pervasive but rarely conserved in enteric bacteria;Raghavan R.;mBio,2012

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