Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation-Reference-Cited by-同舟云学术

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Published:2017-04-07 Issue:4 Volume:3 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Schneider Craig S.¹²³,Xu Qingguo¹⁴^ORCID,Boylan Nicholas J.¹³,Chisholm Jane¹³,Tang Benjamin C.¹³^ORCID,Schuster Benjamin S.¹⁵^ORCID,Henning Andreas¹³,Ensign Laura M.¹²³⁴,Lee Ethan³,Adstamongkonkul Pichet⁵,Simons Brian W.⁶⁷^ORCID,Wang Sho-Yu S.¹³,Gong Xiaoqun¹⁸,Yu Tao¹⁵,Boyle Michael P.⁹,Suk Jung Soo¹⁴⁵,Hanes Justin¹²³⁴⁵

Affiliation:

1. The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

2. Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.

3. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

4. Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.

5. Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

6. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

7. Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

8. School of Life Sciences, Tianjin University, Tianjin 300072, People‘s Republic of China.

9. Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Abstract

Debunking the mucoadhesion myth: Nonsticky particles for enhanced pulmonary drug delivery.

Funder

National Heart, Lung, and Blood Institute

National Cancer Institute

National Institutes of Health

Cystic Fibrosis Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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