The science and medicine of human immunology

Author:

Pulendran Bali12345ORCID,Davis Mark M.1356ORCID

Affiliation:

1. Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA.

2. Department of Pathology, Stanford University, Stanford, CA 94305, USA.

3. Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.

4. Stanford ChEM-H: Chemistry, Engineering and Medicine for Human Health, Stanford University, Stanford, CA 94305, USA.

5. Stanford University School of Medicine, Stanford, CA 94305, USA.

6. Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.

Abstract

Immunology through a human lens The coronavirus disease 2019 (COVID-19) pandemic has underscored the critical need to better understand the human immune system and how to unleash its power to develop vaccines and therapeutics. Much of our knowledge of the immune system has accrued from studies in mice, yet vaccines and drugs that work effectively in mice do not always translate into humans. Pulendran and Davis review recent technological advances that have facilitated the study of the immune system in humans. They discuss new insights and how these can affect the development of drugs and vaccines in the modern era. Science , this issue p. eaay4014

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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