Affiliation:
1. Key Laboratory of Environmental Medicine and Engineering of Ministry of Education School of Public Health Southeast University Nanjing Jiangsu China
2. Department of Nutrition and Food Hygiene School of Public Health Southeast University Nanjing Jiangsu China
3. ZhiShi Plastic Clinic Sanya Hainan China
4. Department of Food Science and Technology Jiangsu Agri‐Animal Husbandry Vocational College Taizhou Jiangsu China
Abstract
AbstractThe interaction between diet and the immune system has garnered considerable attention, especially regarding the immunomodulatory effects of food‐derived peptides. These peptides, derived from dietary proteins, exhibit diverse mechanisms of action, influencing cytokine production, immune cell function, and gut barrier integrity. Although there are numerous in vitro and animal studies supporting its therapeutic potential in immune‐related diseases, clinical relevance requires further investigation. This review synthesizes current knowledge on food‐derived peptides as immunomodulators, highlighting clinical insights and discussing challenges in their application. Additionally, it expands beyond peptides to encompass various dietary compounds influencing immune function. By integrating structural and functional diversity, this review provides a comprehensive understanding of how nutrition shapes immune responses, offering insights for personalized health strategies.
Funder
National Natural Science Foundation of China
China Academy of Space Technology
Southeast University